Isosorbide mononitrate (Monoket): Basics, Side Effects & Reviews - GoodRx What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? Evening primrose. Always consult your healthcare provider. Clipboard, Search History, and several other advanced features are temporarily unavailable. If this worries you, talk to your doctor or pharmacist about other options. 67% of reviewers reported a positive effect, while 13% reported a negative effect. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Mayo Clinic does not endorse companies or products. Clin Res Cardiol. Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. If headaches continue or become severe, tell your doctor promptly. Properly discard this product when it is expired or no longer needed. https://naturalmedicines.therapeuticresearch.com. No, that's not true all the time. Accessed Sept. 7, 2022. PMC Select a condition to view a list of medication options. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. All rights reserved. Integrative medicine (complementary and alternative medicine). https://naturalmedicines.therapeuticresearch.com. If concomitant therapy cannot be avoided, monitor clinical effects of the . You need to take it every day in order for it to work. Other side effects not listed may also occur in some patients. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). These side effects may go away during treatment as your body adjusts to the medicine. Follow directions about how much medicine to take. But only about 25% of people who take herbal supplements tell their health care providers. View more. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Natural Medicines. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. B complex. The tablet usually is taken two or three times daily. Isosorbide may cause other side effects. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. Isosorbide mononitrate helps to prevent angina chest pain from developing. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. All rights reserved. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. Cleophas TJ, Niemeyer MG, van Der Wall EE. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Do not share this medication with others. There are 195 drugs known to interact with It will not treat an angina attack that has already begun. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. FOIA Isosorbide mononitrate belongs to the group of medicines called nitrates. Ask your doctor before using aspirin together with alcohol. Accessed Sept. 7, 2022. Isosorbide mononitrate (Monoket) works slowly to help prevent chest pain. It is not intended as medical advice for individual conditions or treatment. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Treatment and prognosis of heart failure with preserved ejection . You may opt-out of email communications at any time by clicking on Imdur vs. Isordil - RxList Do not store in the bathroom. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Browse Drugs and Medicines. This risk may be even higher for certain groups. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Do not take two doses together to make up for a missed dose. Your health care provider and pharmacist can help you stay away from unsafe interactions. St. John's wort. Take the container with you, even if it is empty. Enter other medications to view a detailed report. Nitrates | Prescribing information | Angina | CKS | NICE If you have any problems with the way your liver works, or any problems with the way your kidneys work. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. Natural Medicines. To view a report comparing 3 (or more) medications, please sign in or create an account. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Some don't work well with prescription medicines. Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). May also be prescribed off label for Esophageal Spasm. Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. It works to relax your blood vessels. Yet many herbal supplements may interact with heart disease medicines. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. What happens if I stop taking isosorbide mononitrate (Monoket)? Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. There may be variations in CSA schedules between individual states. Minimally clinically significant. Isosorbide mononitrate is used to prevent chest pain in patients with a certain heart condition (coronary artery disease).This medication belongs to a class of drugs known as nitrates. and transmitted securely. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. Please note that only the generic name of each medication is listed below. It might help to take isosorbide mononitrate and dinitrate after meals. Isosorbide mononitrate. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. Tolerance is more likely to happen if you don't take your dose at the same time every day. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. HHS Vulnerability Disclosure, Help It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. Patient does not provide medical advice, diagnosis or treatment. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. Herbal supplements can strongly affect the body. Danshen. Federal government websites often end in .gov or .mil. Accessed Sept. 7, 2022. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Normal ecg doesn't rule out heart disease. Although not all of these side effects may occur, if they do occur they may need medical attention. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. I took this for 4 days, and my headaches were unbearable. Take them to your local pharmacy which will dispose of them for you. official website and that any information you provide is encrypted Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). The extended-release capsule usually is taken once daily. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Continue to take isosorbide even if you feel well. Along with its needed effects, a medicine may cause some unwanted effects. This product may contain inactive ingredients, which can cause allergic reactions or other problems. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. It is in the nitrate class of drugs. Try our Symptom Checker Got any other symptoms? It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. coma (loss of consciousness for a period of time). All rights reserved. Take the missed dose as soon as you remember it. Diabetes treatment: Can cinnamon lower blood sugar? The Swedish Multicentre Group. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. So get a ct scan brain apart from cardiology workup. Click here for an email preview. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Can isosorbide mononitrate cause problems? In: Current Medical Diagnosis & Treatment 2022. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Discuss the risks and benefits with your doctor. Higher dosages are associated with stomach irritation and Isosorbide mononitrate - UpToDate For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? What special dietary instructions should I follow? Try to keep your regular appointments with your doctor. And as many as 25% of people also take medicines ordered for them by their health care providers, also called prescription medicines. A randomized, double-blind, cross-over study. Seek alternatives to the CYP3A4 substrate when possible. Review/update the Does isosorbide mononitrate (Monoket) affect your kidneys? Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. Isosorbide Mononitrate ER Oral: Uses, Side Effects - WebMD Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Cardizem Alternatives Compared - Drugs.com Limited data from animal studies indicate no adverse effects on the pregnancy or the unborn child.
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